2021 U.S. Open men’s final odds, predictions: Proven tennis expert reveals Djokovic vs. Medvedev picks, bets

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Novak Djokovic is on the brink of history, but Daniil Medvedev won’t go quietly when the two meet Sunday in the 2021 U.S. Open men’s singles final at Arthur Ashe Stadium. World No. 1 and top-seed Djokovic seeks his fourth U.S. Open title and record 21st Grand Slam overall. A win would also make him the first men’s player to win all four Grand Slam titles in the same year since Rod Laver did it in 1969. Medvedev, ranked No. 2 and seeded-second, seeks to become the first Russian to win a Grand Slam since 2005. Medvedev eased past Felix Auger-Aliassime in straight sets in Friday’s semifinals, while Djokovic beat Matteo Berrettini in five sets.      

The match at Arthur Ashe Stadium is scheduled for 4 p.m. ET. The latest Djokovic vs. Medvedev odds from Caesars Sportsbook list Djokovic as the -275 favorite (risk $275 to win $100), while Medvedev is the +230 underdog. The over-under for total games is set at 38.5 in the latest 2021 U.S. Open odds. Before you make any Djokovic vs. Medvedev men’s final picks or 2021 U.S. Open predictions, make sure you check out what expert Sean Calvert has to say.

Calvert is the renowned handicapper who called Stan Wawrinka winning the 2014 Australian Open at 60-1, the last Australian title won by someone other than Novak Djokovic or Roger Federer. In 2019, Calvert took down a huge score on Dominic Thiem winning Indian Wells at 80-1. 

And earlier in 2021, he nailed both of his bets for the Wimbledon men’s singles final: Djokovic to beat Matteo Berrettini three sets to one (+275) and Djokovic to win and both players to win a set (+130). Anyone following his picks is way up.

Now, Calvert has been digging deep into the latest 2021 U.S. Open odds and released his best bets for Djokovic vs. Medvedev. He’s only sharing his expert U.S. Open picks and analysis at SportsLine.

Novak Djokovic vs. Daniil Medvedev preview

Djokovic has won five of the eight meetings,…



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