2022 NFL divisional round picks, odds, prediction, best bets by top model: This four-way parlay pays 12-1

After a super-sized wild card weekend, eight teams will head into the divisional round of the 2022 NFL playoffs with hopes of surviving and advancing the biggest NFL playoff bracket ever. The divisional round NFL schedule will feature Titans vs. Bengals and Packers vs. 49ers on Saturday, while Buccaneers vs. Rams and Chiefs vs. Bills will take place on Sunday. The Bills vs. Chiefs matchup is a rematch of last year’s AFC Championship Game, and the winner of that postseason matchup is likely to be a favorite in the AFC.

The Chiefs are two-point favorites at home in the latest 2022 NFL odds from Caesars Sportsbook despite losing 38-20 at home to the Bills in Week 5. Can the Chiefs overcome the Bills and reach their fourth consecutive conference championship game? Which teams should you back as you put together your divisional round NFL parlays? Before making any NFL playoff picks, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters the 2022 NFL divisional round on an incredible 137-97 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in four confident NFL best bets for the NFL divisional round 2022. If you successfully parlay its picks, you’d be looking at a massive payout of around 12-1. You can only see the model’s NFL playoff picks at SportsLine. 

Top divisional round NFL picks

After simulating every NFL playoff game 10,000 times, the model is high on the 49ers to cover as six-point road underdogs…