NFL Week 8 picks, predictions, schedule, odds, fantasy tips

The Week 8 NFL schedule for the 2025 season brings exciting matchups.
Steelers QB Aaron Rodgers faces his former team when the Packers come to town, the Bills look to avoid losing three straight, and the Giants and Eagles face off in a classic NFC East showdown.
We have you covered with everything you need to know. Our NFL Nation reporters take you inside the locker room with the best thing they heard this week, and ESPN Research provides a key stat to know and a betting nugget for each contest. Plus, analytics writer Seth Walder makes a bold prediction for each matchup, and fantasy analyst Eric Moody shares fantasy football intel. We also have Football Power Index (FPI) matchup quality ratings (out of 100) and game projections, and three analysts — Pamela Maldonado, Moody and Walder — give us final score picks for every game.
Let’s get into the full Week 8 slate, which culminates with a “Monday Night Football” matchup between the Commanders and Chiefs on ESPN. (Game times are Sunday unless otherwise noted.)
Jump to a matchup:
SF-HOU | NYG-PHI | CHI-BAL
BUF-CAR | CLE-NE | NYJ-CIN
MIA-ATL | TB-NO | DAL-DEN
TEN-IND | GB-PIT | WSH-KC
Thursday: MIN-LAC
Bye: DET, LV, LAR, ARI, SEA, JAX
1 p.m. ET | Fox | Matchup rating: 64.7/100
ESPN BET: HOU -1.5 (41.5 O/U)
What we’re hearing on the 49ers: For the first time since DeMeco Ryans left San Francisco to be the Texans’ coach, the Niners will have to face a Ryans-led defense. It’s a tall order, as Houston ranks first in the NFL in scoring defense, second in defensive EPA and fifth in yards per carry allowed (3.8). “You’re going against a very sound defense schematically, a defense that plays the right way with their intent and just how physical they play, and a very talented group of 11 guys, too, with good backups,” coach Kyle Shanahan said. “Everything’s a challenge about it, but it starts with their physicality and soundness.” — Nick Wagoner
What we’re hearing on the Texans: The Texans’ pass catchers might…


