Oleksandr Usyk vs. Anthony Joshua prediction, odds, picks: Boxing expert reveals bets for Aug. 20 title fight

Three of the four major heavyweight belts are at stake Saturday when champion Oleksandr Usyk defends the titles against former champion Anthony Joshua in one of the most anticipated boxing rematches of 2022. The 12-round main event closes the curtain on the pay-per-view main card (noon ET) from King Abdullah Sports City in Jeddah, Saudi Arabia. Last September, Usyk stunned most boxing observers when he dominated Joshua in a 12-round decision to win the belts in just his third fight as a heavyweight. He had previously become a unified champion in the cruiserweight division. The mercurial Joshua suffered the second major upset loss of his career but can return to the top of the sport should he prevail in Saturday’s rematch.

Usyk is listed as a -200 favorite (risk $200 to win $100), while Joshua comes back at +170 in the latest Usyk vs. Joshua II odds at Caesars Sportsbook. The over/under for total rounds completed is 10.5, with the over favored at -140 and the under priced at +120. Before settling any Usyk vs. Joshua II picks, make sure you see the boxing predictions and betting advice from SportsLine combat analyst Brandon Wise.

Wise, who is the combat sports editor for CBS Sports, is an experienced boxing and mixed martial arts analyst who has consistently provided winning selections for SportsLine members. For the past two years, he has hit numerous boxing selections in big-time matchups.

For instance, Wise called for Gervonta Davis to win in Rounds 1-6 (-110) against Rolando Romero for the WBA regular lightweight title in May. Davis scored a sixth-round stoppage to give Wise’s followers another winner, and the under 6.5 rounds (-130) that Wise predicted also connected. Moreover, last November he predicted a stoppage victory between rounds No. 10 and 12 for Canelo Alvarez against Caleb Plant in their super middleweight unification bout. The proposition wager paid +450 and Alvarez stopped…